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A MYLK variant regulates asthmatic inflammation via alterations in mRNA secondary structure

Myosin light-chain kinase (MYLK) is a gene known to be significantly associated with severe asthma in African Americans. Here we further examine the molecular function of a single-nucleotide polymorphism (SNP), located in the non-muscle myosin light-chain kinase isoform (nmMLCK), in asthma susceptib...

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Detalles Bibliográficos
Autores principales: Wang, Ting, Zhou, Tong, Saadat, Laleh, Garcia, Joe GN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795064/
https://www.ncbi.nlm.nih.gov/pubmed/25271083
http://dx.doi.org/10.1038/ejhg.2014.201