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Expression analysis in intestinal mucosa reveals complex relations among genes under the association peaks in celiac disease

Celiac disease is a chronic immune-mediated disorder with an important genetic component. To date, there are 57 independent association signals from 39 non-HLA loci, and a total of 66 candidate genes have been proposed. We aimed to scrutinize the functional implication of 45 of those genes by analyz...

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Detalles Bibliográficos
Autores principales: Plaza-Izurieta, Leticia, Fernandez-Jimenez, Nora, Irastorza, Iñaki, Jauregi-Miguel, Amaia, Romero-Garmendia, Irati, Vitoria, Juan Carlos, Bilbao, Jose Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795102/
https://www.ncbi.nlm.nih.gov/pubmed/25388004
http://dx.doi.org/10.1038/ejhg.2014.244