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A Rapid and Quantitative Flow Cytometry Method for the Analysis of Membrane Disruptive Antimicrobial Activity

We describe a microbial flow cytometry method that quantifies within 3 hours antimicrobial peptide (AMP) activity, termed Minimum Membrane Disruptive Concentration (MDC). Increasing peptide concentration positively correlates with the extent of bacterial membrane disruption and the calculated MDC is...

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Detalles Bibliográficos
Autores principales: O’Brien-Simpson, Neil M., Pantarat, Namfon, Attard, Troy J., Walsh, Katrina A., Reynolds, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795541/
https://www.ncbi.nlm.nih.gov/pubmed/26986223
http://dx.doi.org/10.1371/journal.pone.0151694