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Drug-set enrichment analysis: a novel tool to investigate drug mode of action
Motivation: Automated screening approaches are able to rapidly identify a set of small molecules inducing a desired phenotype from large small-molecule libraries. However, the resulting set of candidate molecules is usually very diverse pharmacologically, thus little insight on the shared mechanism...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795590/ https://www.ncbi.nlm.nih.gov/pubmed/26415724 http://dx.doi.org/10.1093/bioinformatics/btv536 |