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Drug-set enrichment analysis: a novel tool to investigate drug mode of action

Motivation: Automated screening approaches are able to rapidly identify a set of small molecules inducing a desired phenotype from large small-molecule libraries. However, the resulting set of candidate molecules is usually very diverse pharmacologically, thus little insight on the shared mechanism...

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Detalles Bibliográficos
Autores principales:	Napolitano, Francesco, Sirci, Francesco, Carrella, Diego, di Bernardo, Diego
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795590/ https://www.ncbi.nlm.nih.gov/pubmed/26415724 http://dx.doi.org/10.1093/bioinformatics/btv536

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