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The Contribution of Ionic Currents to Rate-Dependent Action Potential Duration and Pattern of Reentry in a Mathematical Model of Human Atrial Fibrillation

Persistent atrial fibrillation (PeAF) in humans is characterized by shortening of action potential duration (APD) and attenuation of APD rate-adaptation. However, the quantitative influences of particular ionic current alterations on rate-dependent APD changes, and effects on patterns of reentry in...

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Detalles Bibliográficos
Autores principales: Lee, Young-Seon, Hwang, Minki, Song, Jun-Seop, Li, Changyong, Joung, Boyoung, Sobie, Eric A., Pak, Hui-Nam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795605/
https://www.ncbi.nlm.nih.gov/pubmed/26964092
http://dx.doi.org/10.1371/journal.pone.0150779