De novo identification of replication-timing domains in the human genome by deep learning

Motivation: The de novo identification of the initiation and termination zones—regions that replicate earlier or later than their upstream and downstream neighbours, respectively—remains a key challenge in DNA replication. Results: Building on advances in deep learning, we developed a novel hybrid a...

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Detalles Bibliográficos
Autores principales: Liu, Feng, Ren, Chao, Li, Hao, Zhou, Pingkun, Bo, Xiaochen, Shu, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795613/
https://www.ncbi.nlm.nih.gov/pubmed/26545821
http://dx.doi.org/10.1093/bioinformatics/btv643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795613/
https://www.ncbi.nlm.nih.gov/pubmed/26545821
http://dx.doi.org/10.1093/bioinformatics/btv643

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