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No Promoter Left Behind (NPLB): learn de novo promoter architectures from genome-wide transcription start sites

Summary: Promoters have diverse regulatory architectures and thus activate genes differently. For example, some have a TATA-box, many others do not. Even the ones with it can differ in its position relative to the transcription start site (TSS). No Promoter Left Behind (NPLB) is an efficient, organi...

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Detalles Bibliográficos
Autores principales: Mitra, Sneha, Narlikar, Leelavati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795619/
https://www.ncbi.nlm.nih.gov/pubmed/26530723
http://dx.doi.org/10.1093/bioinformatics/btv645