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Activation of G Proteins by Guanine Nucleotide Exchange Factors Relies on GTPase Activity

G proteins are an important family of signalling molecules controlled by guanine nucleotide exchange and GTPase activity in what is commonly called an ‘activation/inactivation cycle’. The molecular mechanism by which guanine nucleotide exchange factors (GEFs) catalyse the activation of monomeric G p...

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Detalles Bibliográficos
Autores principales: Stanley, Rob J., Thomas, Geraint M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795700/
https://www.ncbi.nlm.nih.gov/pubmed/26986850
http://dx.doi.org/10.1371/journal.pone.0151861