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Activation of G Proteins by Guanine Nucleotide Exchange Factors Relies on GTPase Activity
G proteins are an important family of signalling molecules controlled by guanine nucleotide exchange and GTPase activity in what is commonly called an ‘activation/inactivation cycle’. The molecular mechanism by which guanine nucleotide exchange factors (GEFs) catalyse the activation of monomeric G p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795700/ https://www.ncbi.nlm.nih.gov/pubmed/26986850 http://dx.doi.org/10.1371/journal.pone.0151861 |