Cisplatin Resistant Spheroids Model Clinically Relevant Survival Mechanisms in Ovarian Tumors

The majority of ovarian tumors eventually recur in a drug resistant form. Using cisplatin sensitive and resistant cell lines assembled into 3D spheroids we profiled gene expression and identified candidate mechanisms and biological pathways associated with cisplatin resistance. OVCAR-8 human ovarian...

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Detalles Bibliográficos
Autores principales: Chowanadisai, Winyoo, Messerli, Shanta M., Miller, Daniel H., Medina, Jamie E., Hamilton, Joshua W., Messerli, Mark A., Brodsky, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795743/
https://www.ncbi.nlm.nih.gov/pubmed/26986722
http://dx.doi.org/10.1371/journal.pone.0151089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795743/
https://www.ncbi.nlm.nih.gov/pubmed/26986722
http://dx.doi.org/10.1371/journal.pone.0151089

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