Phenotypically Dormant and Immature Leukaemia Cells Display Increased Ribosomal Protein S6 Phosphorylation

Mechanistic/mammalian target of rapamycin (mTOR) activity drives a number of key metabolic processes including growth and protein synthesis. Inhibition of the mTOR pathway promotes cellular dormancy. Since cells from patients with acute myeloid leukaemia (AML) can be phenotypically dormant (quiescen...

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Detalles Bibliográficos
Autores principales: Pallis, Monica, Harvey, Tamsin, Russell, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795744/
https://www.ncbi.nlm.nih.gov/pubmed/26985829
http://dx.doi.org/10.1371/journal.pone.0151480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795744/
https://www.ncbi.nlm.nih.gov/pubmed/26985829
http://dx.doi.org/10.1371/journal.pone.0151480

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