The Extracellular and Cytoplasmic Domains of Syndecan Cooperate Postsynaptically to Promote Synapse Growth at the Drosophila Neuromuscular Junction

The heparan sulfate proteoglycan (HSPG) Syndecan (Sdc) is a crucial regulator of synapse development and growth in both vertebrates and invertebrates. In Drosophila, Sdc binds via its extracellular heparan sulfate (HS) sidechains to the receptor protein tyrosine phosphatase LAR to promote the morpho...

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Detalles Bibliográficos
Autores principales: Nguyen, Margaret U., Kwong, Jereen, Chang, Julia, Gillet, Victoria G., Lee, Rachel M., Johnson, Karl Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795781/
https://www.ncbi.nlm.nih.gov/pubmed/26987116
http://dx.doi.org/10.1371/journal.pone.0151621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795781/
https://www.ncbi.nlm.nih.gov/pubmed/26987116
http://dx.doi.org/10.1371/journal.pone.0151621

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