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Penehyclidine Hydrochloride Pretreatment Ameliorates Rhabdomyolysis-Induced AKI by Activating the Nrf2/HO-1 Pathway and Allevi-ating Endoplasmic Reticulum Stress in Rats

Acute kidney injury (AKI) is one of the most severe complications of rhabdomyolysis (RM). The underlying mechanisms and potential preventions need to be investigated. Penehyclidine hydrochloride (PHC) was reported to ameliorate renal ischemia-reperfusion injury, but the effect of PHC on RM-reduced A...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Huang, XuDong, Zhang, LiXia, Yang, XinJun, Wang, LiHui, Chen, YunShuang, Wang, JingHua, Wu, GuangLi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795801/
https://www.ncbi.nlm.nih.gov/pubmed/26987113
http://dx.doi.org/10.1371/journal.pone.0151158