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In cellulo phosphorylation of XRCC4 Ser320 by DNA-PK induced by DNA damage
XRCC4 is a protein associated with DNA Ligase IV, which is thought to join two DNA ends at the final step of DNA double-strand break repair through non-homologous end joining. In response to treatment with ionizing radiation or DNA damaging agents, XRCC4 undergoes DNA-PK-dependent phosphorylation. F...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795952/ https://www.ncbi.nlm.nih.gov/pubmed/26666690 http://dx.doi.org/10.1093/jrr/rrv086 |