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Application of cell sorting for enhancing the performance of the cytokinesis-block micronucleus assay

Among the numerous methods available to assess genotoxicity, the cytokinesis-block micronucleus (CBMN) assay is very popular due its relative simplicity and power to detect both clastogenic and aneugenic compounds. A problem with the CBMN assay is that all DNA damaging agents also inhibit the abilit...

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Detalles Bibliográficos
Autores principales: Nakamura, Ayumi, Monzen, Satoru, Takasugi, Yuki, Wojcik, Andrzej, Mariya, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795957/
https://www.ncbi.nlm.nih.gov/pubmed/26826197
http://dx.doi.org/10.1093/jrr/rrv103