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Sequence-dependent but not sequence-specific piRNA adhesion traps mRNAs to the germ plasm

The conserved Piwi family of proteins and piwi-interacting RNAs (piRNAs) play a central role in genomic stability, which is inextricably tied with germ cell formation, by forming ribonucleoproteins (piRNPs) that silence transposable elements (TEs)(1). In Drosophila melanogaster and other animals, pr...

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Detalles Bibliográficos
Autores principales: Vourekas, Anastassios, Alexiou, Panagiotis, Vrettos, Nicholas, Maragkakis, Manolis, Mourelatos, Zissimos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795963/
https://www.ncbi.nlm.nih.gov/pubmed/26950602
http://dx.doi.org/10.1038/nature17150