Rapamycin Inhibits Cardiac Hypertrophy by Promoting Autophagy via the MEK/ERK/Beclin-1 Pathway

Rapamycin, also known as sirolimus, is an antifungal agent and immunosuppressant drug used to prevent organ rejection in transplantation. However, little is known about the role of rapamycin in cardiac hypertrophy and the signaling pathways involved. Here, the effect of rapamycin was examined using...

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Detalles Bibliográficos
Autores principales: Gu, Jun, Hu, Wei, Song, Zhi-Ping, Chen, Yue-Guang, Zhang, Da-Dong, Wang, Chang-Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796007/
https://www.ncbi.nlm.nih.gov/pubmed/27047390
http://dx.doi.org/10.3389/fphys.2016.00104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796007/
https://www.ncbi.nlm.nih.gov/pubmed/27047390
http://dx.doi.org/10.3389/fphys.2016.00104

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