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Using Incomplete Trios to Boost Confidence in Family Based Association Studies

Most currently available family based association tests are designed to account only for nuclear families with complete genotypes for parents as well as offspring. Due to the availability of increasingly less expensive generation of whole genome sequencing information, genetic studies are able to co...

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Detalles Bibliográficos
Autores principales: Dhankani, Varsha, Gibbs, David L., Knijnenburg, Theo, Kramer, Roger, Vockley, Joseph, Niederhuber, John, Shmulevich, Ilya, Bernard, Brady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796035/
https://www.ncbi.nlm.nih.gov/pubmed/27047537
http://dx.doi.org/10.3389/fgene.2016.00034