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G6PD protects from oxidative damage and improves healthspan in mice

Reactive oxygen species (ROS) are constantly generated by cells and ROS-derived damage contributes to ageing. Protection against oxidative damage largely relies on the reductive power of NAPDH, whose levels are mostly determined by the enzyme glucose-6-phosphate dehydrogenase (G6PD). Here, we report...

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Detalles Bibliográficos
Autores principales: Nóbrega-Pereira, Sandrina, Fernandez-Marcos, Pablo J., Brioche, Thomas, Gomez-Cabrera, Mari Carmen, Salvador-Pascual, Andrea, Flores, Juana M., Viña, Jose, Serrano, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796314/
https://www.ncbi.nlm.nih.gov/pubmed/26976705
http://dx.doi.org/10.1038/ncomms10894