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The effect of amidation on the behaviour of antimicrobial peptides

Aurein 2.6-COOH and aurein 3.1-COOH were studied along with their naturally occurring C-terminally amidated analogues. Circular dichroism (CD) and molecular dynamic (MD) simulations were used to study the effects of amidation on the interaction of antimicrobial peptides (AMPs) with lipid bilayers. C...

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Detalles Bibliográficos
Autores principales: Mura, Manuela, Wang, Jianping, Zhou, Yuhua, Pinna, Marco, Zvelindovsky, Andrei V., Dennison, Sarah R., Phoenix, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796345/
https://www.ncbi.nlm.nih.gov/pubmed/26745958
http://dx.doi.org/10.1007/s00249-015-1094-x