Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist

The inherent disadvantages of using granulocyte colony-stimulating factor (G-CSF) for hematopoietic stem cell (HSC) mobilization have driven efforts to identify alternate strategies based on single doses of small molecules. Here, we show targeting α(9)β(1)/α(4)β(1) integrins with a single dose of a...

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Detalles Bibliográficos
Autores principales: Cao, Benjamin, Zhang, Zhen, Grassinger, Jochen, Williams, Brenda, Heazlewood, Chad K., Churches, Quentin I., James, Simon A., Li, Songhui, Papayannopoulou, Thalia, Nilsson, Susan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796355/
https://www.ncbi.nlm.nih.gov/pubmed/26975966
http://dx.doi.org/10.1038/ncomms11007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796355/
https://www.ncbi.nlm.nih.gov/pubmed/26975966
http://dx.doi.org/10.1038/ncomms11007

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