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Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist
The inherent disadvantages of using granulocyte colony-stimulating factor (G-CSF) for hematopoietic stem cell (HSC) mobilization have driven efforts to identify alternate strategies based on single doses of small molecules. Here, we show targeting α(9)β(1)/α(4)β(1) integrins with a single dose of a...
Autores principales: | Cao, Benjamin, Zhang, Zhen, Grassinger, Jochen, Williams, Brenda, Heazlewood, Chad K., Churches, Quentin I., James, Simon A., Li, Songhui, Papayannopoulou, Thalia, Nilsson, Susan K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796355/ https://www.ncbi.nlm.nih.gov/pubmed/26975966 http://dx.doi.org/10.1038/ncomms11007 |
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