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Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments

Cell migration has two opposite faces: although necessary for physiological processes such as immune responses, it can also have detrimental effects by enabling metastatic cells to invade new organs. In vivo, migration occurs in complex environments and often requires a high cellular deformability,...

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Detalles Bibliográficos
Autores principales: Thiam, Hawa-Racine, Vargas, Pablo, Carpi, Nicolas, Crespo, Carolina Lage, Raab, Matthew, Terriac, Emmanuel, King, Megan C., Jacobelli, Jordan, Alberts, Arthur S., Stradal, Theresia, Lennon-Dumenil, Ana-Maria, Piel, Matthieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796365/
https://www.ncbi.nlm.nih.gov/pubmed/26975831
http://dx.doi.org/10.1038/ncomms10997