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Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma

Epidermal growth factor receptor (EGFR) is a key molecule in the pathophysiology of oesophageal squamous cell carcinoma (OSCC). However, EGFR-targeted agents such as anti-EGFR antibody or tyrosine kinase inhibitors for OSCC have not demonstrated any clinical benefits. Recently, a novel chemotherapeu...

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Detalles Bibliográficos
Autores principales: Kikuchi, Osamu, Ohashi, Shinya, Horibe, Tomohisa, Kohno, Masayuki, Nakai, Yukie, Miyamoto, Shin’ichi, Chiba, Tsutomu, Muto, Manabu, Kawakami, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796678/
https://www.ncbi.nlm.nih.gov/pubmed/26956916
http://dx.doi.org/10.1038/srep22452