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Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na(+)/K(+)-ATPase
Glycoprotein nonmetastatic melanoma protein B (GPNMB) plays important roles in various types of cancer and amyotrophic lateral sclerosis (ALS). The details of GPNMB function and its interacting protein have not been clarified. Therefore, to identify GPNMB binding partners on the cell membrane, we us...
Autores principales: | Ono, Yoko, Tsuruma, Kazuhiro, Takata, Masafumi, Shimazawa, Masamitsu, Hara, Hideaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796790/ https://www.ncbi.nlm.nih.gov/pubmed/26988030 http://dx.doi.org/10.1038/srep23241 |
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