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Identification of Potential Drug Targets in Cancer Signaling Pathways using Stochastic Logical Models

The investigation of vulnerable components in a signaling pathway can contribute to development of drug therapy addressing aberrations in that pathway. Here, an original signaling pathway is derived from the published literature on breast cancer models. New stochastic logical models are then develop...

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Detalles Bibliográficos
Autores principales: Zhu, Peican, Aliabadi, Hamidreza Montazeri, Uludağ, Hasan, Han, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796823/
https://www.ncbi.nlm.nih.gov/pubmed/26988076
http://dx.doi.org/10.1038/srep23078