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Identification of Potential Drug Targets in Cancer Signaling Pathways using Stochastic Logical Models
The investigation of vulnerable components in a signaling pathway can contribute to development of drug therapy addressing aberrations in that pathway. Here, an original signaling pathway is derived from the published literature on breast cancer models. New stochastic logical models are then develop...
Autores principales: | Zhu, Peican, Aliabadi, Hamidreza Montazeri, Uludağ, Hasan, Han, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796823/ https://www.ncbi.nlm.nih.gov/pubmed/26988076 http://dx.doi.org/10.1038/srep23078 |
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