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Exploring regulatory networks of miR-96 in the developing inner ear

Mutations in the microRNA Mir96 cause deafness in mice and humans. In the diminuendo mouse, which carries a single base pair change in the seed region of miR-96, the sensory hair cells crucial for hearing fail to develop fully and retain immature characteristics, suggesting that miR-96 is important...

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Detalles Bibliográficos
Autores principales: Lewis, Morag A., Buniello, Annalisa, Hilton, Jennifer M., Zhu, Fei, Zhang, William I., Evans, Stephanie, van Dongen, Stijn, Enright, Anton J., Steel, Karen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796898/
https://www.ncbi.nlm.nih.gov/pubmed/26988146
http://dx.doi.org/10.1038/srep23363