Cargando…
Exploring regulatory networks of miR-96 in the developing inner ear
Mutations in the microRNA Mir96 cause deafness in mice and humans. In the diminuendo mouse, which carries a single base pair change in the seed region of miR-96, the sensory hair cells crucial for hearing fail to develop fully and retain immature characteristics, suggesting that miR-96 is important...
Autores principales: | Lewis, Morag A., Buniello, Annalisa, Hilton, Jennifer M., Zhu, Fei, Zhang, William I., Evans, Stephanie, van Dongen, Stijn, Enright, Anton J., Steel, Karen P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796898/ https://www.ncbi.nlm.nih.gov/pubmed/26988146 http://dx.doi.org/10.1038/srep23363 |
Ejemplares similares
-
An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice
por: Lewis, Morag A, et al.
Publicado: (2009) -
The Effect of a Pex3 Mutation on Hearing and Lipid Content of the Inner Ear
por: Kochaj, Rafael M., et al.
Publicado: (2022) -
A reduction in Ptprq associated with specific features of the deafness phenotype of the miR-96 mutant mouse diminuendo
por: Chen, Jing, et al.
Publicado: (2014) -
Hearing impairment due to Mir183/96/182 mutations suggests both loss-of-function and gain-of-function effects
por: Lewis, Morag A., et al.
Publicado: (2021) -
Expression and Replication Studies to Identify New Candidate Genes Involved in Normal Hearing Function
por: Girotto, Giorgia, et al.
Publicado: (2014)