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PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice

Estrogens act in the ventromedial hypothalamic nucleus (VMH) to regulate body weight homeostasis. However, the molecular mechanisms underlying these estrogenic effects are unknown. We show that activation of estrogen receptor-α (ERα) stimulates neural firing of VMH neurons expressing ERα, and these...

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Detalles Bibliográficos
Autores principales: Saito, Kenji, He, Yanlin, Yang, Yongjie, Zhu, Liangru, Wang, Chunmei, Xu, Pingwen, Hinton, Antentor Othrell, Yan, Xiaofeng, Zhao, Jean, Fukuda, Makoto, Tong, Qingchun, Clegg, Deborah J., Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796901/
https://www.ncbi.nlm.nih.gov/pubmed/26988598
http://dx.doi.org/10.1038/srep23459