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Sex-specific genetic effects associated with pigmentation, sensitivity to sunlight, and melanoma in a population of Spanish origin

BACKGROUND: Human pigmentation is a polygenic quantitative trait with high heritability. In addition to genetic factors, it has been shown that pigmentation can be modulated by oestrogens and androgens via up- or down-regulation of melanin synthesis. Our aim was to identify possible sex differences...

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Detalles Bibliográficos
Autores principales: Hernando, Barbara, Ibarrola-Villava, Maider, Fernandez, Lara P., Peña-Chilet, Maria, Llorca-Cardeñosa, Marta, Oltra, Sara S., Alonso, Santos, Boyano, Maria Dolores, Martinez-Cadenas, Conrado, Ribas, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797181/
https://www.ncbi.nlm.nih.gov/pubmed/26998216
http://dx.doi.org/10.1186/s13293-016-0070-1