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EMERGE: a flexible modelling framework to predict genomic regulatory elements from genomic signatures

Regulatory DNA elements, short genomic segments that regulate gene expression, have been implicated in developmental disorders and human disease. Despite this clinical urgency, only a small fraction of the regulatory DNA repertoire has been confirmed through reporter gene assays. The overall success...

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Detalles Bibliográficos
Autores principales: van Duijvenboden, Karel, de Boer, Bouke A., Capon, Nicolas, Ruijter, Jan M., Christoffels, Vincent M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797259/
https://www.ncbi.nlm.nih.gov/pubmed/26531828
http://dx.doi.org/10.1093/nar/gkv1144