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EMERGE: a flexible modelling framework to predict genomic regulatory elements from genomic signatures
Regulatory DNA elements, short genomic segments that regulate gene expression, have been implicated in developmental disorders and human disease. Despite this clinical urgency, only a small fraction of the regulatory DNA repertoire has been confirmed through reporter gene assays. The overall success...
Autores principales: | van Duijvenboden, Karel, de Boer, Bouke A., Capon, Nicolas, Ruijter, Jan M., Christoffels, Vincent M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797259/ https://www.ncbi.nlm.nih.gov/pubmed/26531828 http://dx.doi.org/10.1093/nar/gkv1144 |
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