Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination

We have recently identified lens epithelium-derived growth factor (LEDGF/p75, also known as PSIP1) as a component of the homologous recombination DNA repair machinery. Through its Pro-Trp-Trp-Pro (PWWP) domain, LEDGF/p75 binds to histone marks associated with active transcription and promotes DNA en...

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Detalles Bibliográficos
Autores principales: Baude, Annika, Aaes, Tania Løve, Zhai, Beibei, Al-Nakouzi, Nader, Oo, Htoo Zarni, Daugaard, Mads, Rohde, Mikkel, Jäättelä, Marja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797281/
https://www.ncbi.nlm.nih.gov/pubmed/26721387
http://dx.doi.org/10.1093/nar/gkv1526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797281/
https://www.ncbi.nlm.nih.gov/pubmed/26721387
http://dx.doi.org/10.1093/nar/gkv1526

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