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PON-mt-tRNA: a multifactorial probability-based method for classification of mitochondrial tRNA variations
Transfer RNAs (tRNAs) are essential for encoding the transcribed genetic information from DNA into proteins. Variations in the human tRNAs are involved in diverse clinical phenotypes. Interestingly, all pathogenic variations in tRNAs are located in mitochondrial tRNAs (mt-tRNAs). Therefore, it is cr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797295/ https://www.ncbi.nlm.nih.gov/pubmed/26843426 http://dx.doi.org/10.1093/nar/gkw046 |