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Reversible acetylation on Lys501 regulates the activity of RNase II

RNase II, a 3′ to 5′ processive exoribonuclease, is the major hydrolytic enzyme in Escherichia coli accounting for ∼90% of the total activity. Despite its importance, little is actually known about regulation of this enzyme. We show here that one residue, Lys501, is acetylated in RNase II. This modi...

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Detalles Bibliográficos
Autores principales: Song, Limin, Wang, Guangyuan, Malhotra, Arun, Deutscher, Murray P., Liang, Wenxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797298/
https://www.ncbi.nlm.nih.gov/pubmed/26847092
http://dx.doi.org/10.1093/nar/gkw053