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Small activating RNA binds to the genomic target site in a seed-region-dependent manner

RNA activation (RNAa) is the upregulation of gene expression by small activating RNAs (saRNAs). In order to investigate the mechanism by which saRNAs act in RNAa, we used the progesterone receptor (PR) gene as a model, established a panel of effective saRNAs and assessed the involvement of the sense...

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Detalles Bibliográficos
Autores principales: Meng, Xing, Jiang, Qian, Chang, Nannan, Wang, Xiaoxia, Liu, Chujun, Xiong, Jingwei, Cao, Huiqing, Liang, Zicai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797303/
https://www.ncbi.nlm.nih.gov/pubmed/26873922
http://dx.doi.org/10.1093/nar/gkw076