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Substrate recognition and cleavage-site selection by a single-subunit protein-only RNase P

RNase P is the enzyme that removes 5′ extensions from tRNA precursors. With its diversity of enzyme forms—either protein- or RNA-based, ranging from single polypeptides to multi-subunit ribonucleoproteins—the RNase P enzyme family represents a unique model system to compare the evolution of enzymati...

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Detalles Bibliográficos
Autores principales: Brillante, Nadia, Gößringer, Markus, Lindenhofer, Dominik, Toth, Ursula, Rossmanith, Walter, Hartmann, Roland K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797305/
https://www.ncbi.nlm.nih.gov/pubmed/26896801
http://dx.doi.org/10.1093/nar/gkw080