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αCP binding to a cytosine-rich subset of polypyrimidine tracts drives a novel pathway of cassette exon splicing in the mammalian transcriptome

Alternative splicing (AS) is a robust generator of mammalian transcriptome complexity. Splice site specification is controlled by interactions of cis-acting determinants on a transcript with specific RNA binding proteins. These interactions are frequently localized to the intronic U-rich polypyrimid...

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Detalles Bibliográficos
Autores principales: Ji, Xinjun, Park, Juw Won, Bahrami-Samani, Emad, Lin, Lan, Duncan-Lewis, Christopher, Pherribo, Gordon, Xing, Yi, Liebhaber, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797308/
https://www.ncbi.nlm.nih.gov/pubmed/26896798
http://dx.doi.org/10.1093/nar/gkw088