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Underlying Mechanisms of Memory Deficits Induced by Etomidate Anesthesia in Aged Rat Model: Critical Role of Immediate Early Genes

BACKGROUND: Etomidate (R-1-[1-ethylphenyl] imidazole-5-ethyl ester) is a widely used anesthetic drug that had been reported to contribute to cognitive deficits after general surgery. However, its underlying mechanisms have not been fully elucidated. In this study, we aimed to explore the neurobiolog...

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Detalles Bibliográficos
Autores principales: Li, Xu, Lu, Fen, Li, Wei, Xu, Jun, Sun, Xiao-Jing, Qin, Ling-Zhi, Zhang, Qian-Lin, Yao, Yong, Yu, Qing-Kai, Liang, Xin-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797542/
https://www.ncbi.nlm.nih.gov/pubmed/26712432
http://dx.doi.org/10.4103/0366-6999.172570