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CA3 Synaptic Silencing Attenuates Kainic Acid-Induced Seizures and Hippocampal Network Oscillations123

Epilepsy is a neurological disorder defined by the presence of seizure activity, manifest both behaviorally and as abnormal activity in neuronal networks. An established model to study the disorder in rodents is the systemic injection of kainic acid, an excitatory neurotoxin that at low doses quickl...

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Detalles Bibliográficos
Autores principales: Yu, Lily M. Y., Polygalov, Denis, Wintzer, Marie E., Chiang, Ming-Ching, McHugh, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797997/
https://www.ncbi.nlm.nih.gov/pubmed/27022627
http://dx.doi.org/10.1523/ENEURO.0003-16.2016