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Immunological Functions of the Membrane Proximal Region of MHC Class II Molecules

Major histocompatibility complex (MHC) class II molecules present exogenously derived antigen peptides to CD4 T cells, driving activation of naïve T cells and supporting CD4-driven immune functions. However, MHC class II molecules are not inert protein pedestals that simply bind and present peptides...

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Detalles Bibliográficos
Autores principales: Harton, Jonathan, Jin, Lei, Hahn, Amy, Drake, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798158/
https://www.ncbi.nlm.nih.gov/pubmed/27006762
http://dx.doi.org/10.12688/f1000research.7610.1