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Streptococcus pneumoniae Cell-Wall-Localized Phosphoenolpyruvate Protein Phosphotransferase Can Function as an Adhesin: Identification of Its Host Target Molecules and Evaluation of Its Potential as a Vaccine

In Streptococcus pneumonia, phosphoenolpyruvate protein phosphotransferase (PtsA) is an intracellular protein of the monosaccharide phosphotransferase systems. Biochemical and immunostaining methods were applied to show that PtsA also localizes to the bacterial cell-wall. Thus, it was suspected that...

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Detalles Bibliográficos
Autores principales: Mizrachi Nebenzahl, Yaffa, Blau, Karin, Kushnir, Tatyana, Shagan, Marilou, Portnoi, Maxim, Cohen, Aviad, Azriel, Shalhevet, Malka, Itai, Adawi, Asad, Kafka, Daniel, Dotan, Shahar, Guterman, Gali, Troib, Shany, Fishilevich, Tali, Gershoni, Jonathan M, Braiman, Alex, Mitchell, Andrea M, Mitchell, Timothy J, Porat, Nurith, Goliand, Inna, Chalifa Caspi, Vered, Swiatlo, Edwin, Tal, Michael, Ellis, Ronald, Elia, Natalie, Dagan, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798226/
https://www.ncbi.nlm.nih.gov/pubmed/26990554
http://dx.doi.org/10.1371/journal.pone.0150320