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Impact of Superoxide Dismutase Mimetic AEOL 10150 on the Endothelin System of Fischer 344 Rats

Endothelin-1 is a potent vasoconstrictor and mitogenic peptide involved in the regulation of vasomotor tone and maintenance of blood pressure. Oxidative stress activates the endothelin system, and is implicated in pulmonary and cardiovascular diseases including hypertension, congestive heart failure...

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Detalles Bibliográficos
Autores principales: Ganesh, Devi, Kumarathasan, Prem, Thomson, Errol M., St-Germain, Carly, Blais, Erica, Crapo, James, Vincent, Renaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798617/
https://www.ncbi.nlm.nih.gov/pubmed/26990293
http://dx.doi.org/10.1371/journal.pone.0151810