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Swi1(Timeless) Prevents Repeat Instability at Fission Yeast Telomeres

Genomic instability associated with DNA replication stress is linked to cancer and genetic pathologies in humans. If not properly regulated, replication stress, such as fork stalling and collapse, can be induced at natural replication impediments present throughout the genome. The fork protection co...

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Detalles Bibliográficos
Autores principales: Gadaleta, Mariana C., Das, Mukund M., Tanizawa, Hideki, Chang, Ya-Ting, Noma, Ken-ichi, Nakamura, Toru M., Noguchi, Eishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798670/
https://www.ncbi.nlm.nih.gov/pubmed/26990647
http://dx.doi.org/10.1371/journal.pgen.1005943