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Potency of Full- Length MGF to Induce Maximal Activation of the IGF-I R Is Similar to Recombinant Human IGF-I at High Equimolar Concentrations

AIMS: To compare full-length mechano growth factor (full-length MGF) with human recombinant insulin-like growth factor-I (IGF-I) and human recombinant insulin (HI) in their ability to activate the human IGF-I receptor (IGF-IR), the human insulin receptor (IR-A) and the human insulin receptor-B (IR-B...

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Detalles Bibliográficos
Autores principales: Janssen, Joseph A. M. J. L., Hofland, Leo J., Strasburger, Christian J., van den Dungen, Elisabeth S. R., Thevis, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798685/
https://www.ncbi.nlm.nih.gov/pubmed/26991004
http://dx.doi.org/10.1371/journal.pone.0150453