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Experimental Neuromyelitis Optica Induces a Type I Interferon Signature in the Spinal Cord

Neuromyelitis optica (NMO) is an acute inflammatory disease of the central nervous system (CNS) which predominantly affects spinal cord and optic nerves. Most patients harbor pathogenic autoantibodies, the so-called NMO-IgGs, which are directed against the water channel aquaporin 4 (AQP4) on astrocy...

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Detalles Bibliográficos
Autores principales: Oji, Satoru, Nicolussi, Eva-Maria, Kaufmann, Nathalie, Zeka, Bleranda, Schanda, Kathrin, Fujihara, Kazuo, Illes, Zsolt, Dahle, Charlotte, Reindl, Markus, Lassmann, Hans, Bradl, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798752/
https://www.ncbi.nlm.nih.gov/pubmed/26990978
http://dx.doi.org/10.1371/journal.pone.0151244