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Experimental Neuromyelitis Optica Induces a Type I Interferon Signature in the Spinal Cord
Neuromyelitis optica (NMO) is an acute inflammatory disease of the central nervous system (CNS) which predominantly affects spinal cord and optic nerves. Most patients harbor pathogenic autoantibodies, the so-called NMO-IgGs, which are directed against the water channel aquaporin 4 (AQP4) on astrocy...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798752/ https://www.ncbi.nlm.nih.gov/pubmed/26990978 http://dx.doi.org/10.1371/journal.pone.0151244 |