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Hydrophobicity of Antifungal β-Peptides Is Associated with Their Cytotoxic Effect on In Vitro Human Colon Caco-2 and Liver HepG2 Cells

The widespread distribution of fungal infections, with their high morbidity and mortality rate, is a global public health problem. The increase in the population of immunocompromised patients combined with the selectivity of currents treatments and the emergence of drug-resistant fungal strains are...

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Detalles Bibliográficos
Autores principales: Mora-Navarro, Camilo, Méndez-Vega, Janet, Caraballo-León, Jean, Lee, Myung-ryul, Palecek, Sean, Torres-Lugo, Madeline, Ortiz-Bermúdez, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798767/
https://www.ncbi.nlm.nih.gov/pubmed/26992117
http://dx.doi.org/10.1371/journal.pone.0149271